Filippo Fortis
In 2025, everyone is talking about exosomes and what they might do for anti-aging and hair growth. When it comes to improving the appearance of fine lines and wrinkles and boosting hair growth, exosomes are potent forces. That’s partially because they’re packed with growth factors, which are made of peptides that help your body stimulate cell proliferation and heal wounds. When growth factors are whipped into serums, they can do incredible things for your skin care routine, too.
“Growth factor serums contain ingredients that signal various mechanisms in the skin to repair cellular damage and promote the induction of collagen and elastin,” says dermatologist Dr. Claire Wolinsky. When you use growth factor serums, they may lead to plumper, tighter skin.
If you’re looking for an extra tightening boost for your skin care routine (without turning to neurotoxins like Botox), it might be a good idea to try using a growth factor serum. Below, we rounded up the ten best growth factor serums out there, based on editor favorites and rave online reviews.
BEST FOR ANTI-AGING
Dr. Diamond’s Metacine Instafacial Plasma
You can’t get a PRP injection at home, but this growth factor-packed serum gets pretty close. Dr. Diamond’s Metacine Instafacial Plasma is made with growth factors that closely resemble those found in our bodies. It’s also made with sodium hyaluronate to plump and hydrate skin while it stimulates.
Key ingredients: Bioengineered human identical growth factors, sodium hyaluronate
Skin types: Mature, dry
Bluemercury rating: 4.6/5 stars
An ELLE editor says: “I am convinced this serum is made with magic. It works so well to plump skin and make it feel firmer and more elastic. I’ve gone through two bottles (which is big for me, as someone who never finishes skin care).”—Katie Berohn
