Skip to content
Translation missing: en.INSTAFACIAL® INFUSION

INSTAFACIAL® INFUSION

Biomimetic Microcollagen Matrix Serum

Key Benefits
  • Lift, Firm & Define: microcollagen peptides visibly plump & hydrate the skin, improving the appearance of double chin & facial sagging
  • Structural Support: supports collagen synthesis, for a more defined & sculpted skin
  • Hydration: delivers immediate hydration while supporting smoother & plumper skin over time
  • Barrier Resilience: defends against environmental stressors & soothes irritation
  • Non-greasy finish that absorbs seamlessly & layers beautifully under makeup
  • Vegan & Fragrance-Free: designed for all skin types, including sensitive skin

Description

Inspired by the Micronized Collagen Mask, the last step of Dr. Diamond's signature InstaFacial®, Infusion is formulated with a proprietary matrix of three bioengineered, human-identical microcollagen peptides designed for skin recognition & optimal absorption to support skin’s structural foundation. This lightweight gel serum supports the skin's collagen architecture, improves skin elasticity & visibly firms, lifts & defines facial contours while delivering lasting hydration. Skin appears smoother & more resilient with continued use.

Key Ingredients
  • Biomimetic Microcollagen Matrix: a proprietary network of three microcollagen peptides that support collagen synthesis, firmness, elasticity & overall skin structure
  • Synergistic Signaling Peptides: a network of signaling peptides work to firm the dermal layer, boost hydration, support collagen production & reinforce skin’s structural integrity
  • Sodium Hyaluronate: delivers immediate hydration & visible plumping while supporting skin suppleness
  • Red Macroalgae + Proteoglycans: Antioxidant-rich red macroalgae & proteoglycans help support collagen & elastin fiber networks

View Full List

O WATER ● GLYCERIN O DIMETHICONE O PENTYLENE GLYCOL O PROPANEDIOL ● NIACINAMIDE O SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL ● GIGARTINA STELLATA EXTRACT ● SOLUBLE PROTEOGLYCAN ● MYRISTOYL PENTAPEPTIDE-11 ● SH-POLYPEPTIDE-121 ● SH-POLYPEPTIDE-123 ● SR-(SH-POLYPEPTIDE-69 DIPEPTIDE-19) ● ACETYL TRIPEPTIDE-108 N-ACETYL LYSYL GLUTAMINE ● MYRISTOYL PENTAPEPTIDE-8 O SQUALANE ● SODIUM HYALURONATE O TREHALOSE ● DIAMOND POWDER O DIMETHICONE CROSSPOLYMER ● BETA-GLUCAN ● HORDEUM VULGARE SEED EXTRACT O PHOSPHOLIPIDS O XANTHAN GUM O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMEHTYL TAURATE COPOLYMER O BUTYLENE GLYCOL O POLYSORBATE 60 O PHENOXYETHANOL O CAPRYLYL GLYCOL O CHLORPHENESIN O 1,2-HEXANEDIOL O SODIUM BENZOATE O GLYCERYL CAPRYLATE O GLYCERYL UNDECYLENATE O POTASSIUM SORBATE

How to Use

AM + PM Apply 1-2 pumps on slightly damp skin. Apply a thin layer to face, neck & décolleté.

Optimal Results: Use after Plasma in AM + PM & follow with Emulsion in PM.

Discovery size products are final sale & non-returnable.

Pairs well with

Translation missing: en.INSTAFACIAL® PLASMA

INSTAFACIAL® PLASMA

3 sizes
$35 - $200
Translation missing: en.INSTAFACIAL® EMULSION

INSTAFACIAL® EMULSION

3 sizes
$50 - $350
Translation missing: en.HYDR/O

HYDR/O

2 Sizes
$35 - $300
Translation missing: en.EyeLift

EyeLift

2 sizes
$50 - $225
Translation missing: en.INSTAFACIAL® COLLECTION DUO

INSTAFACIAL® COLLECTION DUO

2 sizes
$85 - $550
Translation missing: en.INSTAFACIAL® COLLECTION TRIO

INSTAFACIAL® COLLECTION TRIO

1 size
$875

CLINICALLY PROVEN.
BACKED BY SCIENCE.

Independent clinical study of 39 participants representing all skin types on the Fitzpatrick scale. Clinical evaluations were conducted after 8 & 12 weeks of using InstaFacial® Infusion.

Before & Afters shown at 12 weeks.

  • 81% had improvement in skin extensibility (softness & suppleness) after 12 weeks, measured by Cutometer Dual MPA 580.4
  • 88% reported their skin looked lifted & firmer after 12 weeks.5
  • 84% reported their cheeks looked fuller & lifted after 12 weeks.5
  • 72% reported their neck looked smoother & less crepey after 12 weeks.5
  • 69% reported their jawline looked lifted & contoured after 12 weeks.5

Lifted & Contoured Jaw

Image alt text not provided
Before
Image alt text not provided
After

Crepey Skin

Image alt text not provided
Before
Image alt text not provided
After

Lifted & Contoured

Image alt text not provided
Before
Image alt text not provided
After

Lifted

Image alt text not provided
Before
Image alt text not provided
After

INFORMED BY MEDICINE. MADE WITH TECHNOLOGY.

  • CLINICAL INSPIRATION

    The final step of the signature Diamond InstaFacial® is a medical-grade, micronized collagen mask designed to support skin recovery, hydration & rejuvenation. Inspired by this final step, InstaFacial® Infusion was developed to support skin’s structural foundation through a next-generation approach to topical collagen. Powered by novel, bioengineered, human-identical microcollagen peptides, Infusion supports collagen synthesis in skin for improved firmness, elasticity, hydration to lift, firm & define facial silhouettes.

  • COLLAGEN, ACTIVATED

    Topical collagen has traditionally been sourced from animals; bovine collagen is about 80% similar to human collagen. Collagen proteins from animals are large & not easily absorbed through skin, thus it typically has to be hydrolyzed or broken down into fragments in order to be utilized in topical skincare products. 

    InstaFacial® Infusion differentiates as it uses a new-to-market technology of bioengineered collagen peptides that are 100% identical to human collagen & utilize the most significant portions of the larger collagen protein but in smaller peptides that the body recognizes as self & can be easily absorbed topically. 

    Infusion’s Biomimetic Collagen Matrix is composed of three bioengineered, human-identical microcollagen peptides designed for optimal skin recognition & absorption. These advanced peptides support the synthesis of Types I & III collagen (I provides structural & tensile strength while III supports flexibility & elasticity), which are the types most closely associated with youthful, healthy-looking skin.

  • PRECISELY ENGINEERED

    Infusion's Biomimetic Microcollagen Peptides are human-identical, meaning they are bioengineered to mimic collagen peptides naturally found in the skin, allowing them to be recognized & absorbed to work in harmony with the skin’s biological processes.

  • CLINICALLY PROVEN

    An independent ex-vivo human skin study evaluated InstaFacial® Infusion’s Microcollagen Matrix (MCM-3) & observed statistically significant increases in key collagen markers in human skin. In the group treated with Microcollagen Matrix (MCM-3) vs. a vehicle control:

    • Collagen gene expression of COL1A1 increased by 140% vs. control
    • Collagen gene expression of COL3A1 increased by 130% vs. control
    • Collagen protein production of Procollagen 1 protein levels increased by 40% vs. control
  • MOLECULAR SYNERGY

    InstaFacial® Infusion’s biomimetic Microcollagen Matrix is supported by a network of complementary technologies designed to address multiple dimensions of skin structure & resilience. Signaling peptides reinforce skin’s structural integrity, while antioxidant-rich red macroalgae, proteoglycans & beta-glucan support collagen & elastin fiber networks. Sodium hyaluronate replenishes hydration & maintains skin suppleness. Together, these technologies work synergistically to support collagen architecture, elasticity & hydration for a firmer, lifted & contoured appearance.

COLLAGEN RE-ENGINEERED:
THE BIOMIMETIC MICROCOLLAGEN MATRIX.

See The Science
  • COLLAGEN NETWORK SUPPORT

    Bioengineered & bioidentical to human Type XXI collagen, a rare but essential collagen involved in supporting the organization & assembly of the skin's collagen network. As a precursor to Types I & III collagen, it serves as a biological scaffold, supporting skin structure, strength & elasticity.

  • ELASTICITY SUPPORT

    A bioengineered, human-identical microcollagen peptide modeled after Type III collagen, a key structural collagen responsible for skin's elasticity, suppleness & youthful resilience.

  • OPTIMAL ABSORPTION

    A low molecular weight recombinant microcollagen peptide designed for enhanced skin absorption, supporting collagen-rich skin & improving the appearance of firmness and elasticity.

See The Science

A ROUTINE ENGINEERED FOR RESULTS.

INSTAFACIAL® PLASMA

Bioactive Growth Factor Serum

A serum inspired by platelet-rich plasma (PRP), a key modality in the Diamond InstaFacial®, featuring five different types of bioengineered, human-identical growth factors, signaling peptides & hyaluronic acid to support the skin's natural repair & rejuvenation.

HOW TO USE: After cleansing, gently press 2-3 drops on slightly damp skin. Apply on face, neck & décolleté.

Learn More

Frequently Asked Questions

See All Faqs

How is Infusion different from traditional collagen skincare?

Traditional collagen ingredients are often too large to effectively interact with the skin. Infusion features bioengineered, human-identical microcollagen peptides specifically designed to be recognized & absorbed by the skin to support collagen-related pathways responsible for firmness, elasticity & structure.

What is Biomimetic Microcollagen Matrix?

Biomimetic Microcollagen Matrix is a proprietary blend of three bioengineered, human-identical microcollagen peptides supported by signaling peptides, proteoglycans, red macroalgae, beta-glucan & hyaluronic acid. Together, these technologies help support the skin's collagen architecture, hydration, elasticity & resilience.

What are biomimetic ingredients?

Biomimetic ingredients are human-identical, mimicking the structure & function of natural compounds found in the human body. Biomimetic ingredients are bioengineered in labs, not derived from plants or animals.

What concerns does Infusion help address?

Infusion helps improve the appearance of skin laxity, loss of firmness, dehydration, fine lines & overall skin quality by supporting collagen synthesis & structural integrity.

When should I use Infusion?

Apply Infusion after Plasma. In the mornings, follow Infusion with HYDR/O & in the evenings, apply Emulsion after Infusion followed by HYDR/O. It can be used daily as part of your regular skincare routine.

Can I use Infusion with Plasma + Emulsion?

Yes, Infusion was specifically designed to work synergistically with the InstaFacial® Collection. Plasma helps support cellular communication, Emulsion supports renewal & Infusion helps reinforce collagen architecture for a comprehensive approach to rejuvenation.

Is Infusion a moisturizer?

While Infusion provides hydration, it is primarily a collagen treatment designed to support skin structure and firmness. For optimal hydration & barrier support, we recommend using HYDR/O.

Is Infusion vegan?

Yes, Infusion is vegan & does not contain animal-derived collagen. Instead, it is formulated with bioengineered, human-identical microcollagen peptides produced through advanced biotechnology. These peptides are designed to mimic key collagen structures found in the skin while supporting collagen-related pathways responsible for firmness, elasticity & skin resilience.

Can I use Infusion after a cosmetic procedure?

Yes, Infusion was inspired by the collagen infusion step of Dr. Diamond's signature InstaFacial® treatment & is designed to support collagen restoration, hydration & skin resilience. As every procedure & recovery timeline is different, we recommend following your physician's post-treatment instructions.

See All Faqs

COMPLETE THE ROUTINE

Overall rating: 4.692623 / 5 from 244 reviews.

AI Generated Review Summary

INSTAFACIAL® INFUSION is a science-backed collagen treatment praised for its lightweight texture and visible skin improvements. Customers appreciate its chic packaging, lightweight feel, and noticeable results in skin radiance, hydration, and reduction of fine lines.

Summary topics

  • Packaging (27%): Customers keep praising the cute and chic packaging, which was mentioned multiple times in the reviews.
  • Texture (19%): Based on many customers, the texture of the product is highly praised for being lightweight and absorbing well into the skin.
  • Skin Appearance (13%): Customers expressed appreciation for how the product made their skin look radiant, healthy, and youthful.
  • Fine Lines and Wrinkles (10%): Customers expressed satisfaction with the ability of this product to reduce fine lines and wrinkles in various skin types.
  • Overall Results (14%): Customers expressed appreciation for the great and amazing results they have experienced using this product. (100% agreement)

Review topics: [size, improvement, weight, issues, wrinkles, quality, absorbs, scent, design, results, skin, works, feels, texture, packaging, price, looks, bottle, ingredients, difference, amount, face, consistency, serum, effects, hydration, formula, lines, appearance, glow].

Review highlights

  • "Nice texture , skin feels so nice and smooth." — Julia
  • "The scent is light and refreshing, and the packaging looks sleek and luxurious." — Brayden
  • "The packaging is cute and simple, the scent is pleasant, and it makes my face feel amazing." — Josephine

Reviews

Good for sensitive skin

"I have pretty reactive skin and this product hasn’t caused any issues. So far my skin feels more balanced and hydrated. Hopefully I’ll see more results soon. My only hesitation to continuing long term use is the cost of the product."

— Malerie T. (4/5)

Infusion my first 2 wks

"I bought the starter pack together with the Plasma and Emulsion. I’m 42 years old, and recently my skin has become much drier and more prone to fine lines and wrinkles. While I haven’t noticed a dramatic visible difference yet, I have noticed that my skin isn’t as dry as it used to be, so that’s already a positive change. That said, I haven’t seen any significant visible improvement yet. However, I’m ready to give it a proper go by purchasing the full-size products and seeing how my skin responds over the next few months."

— Paulina (4/5)

Instinct gratification

"I didn’t think this was going to be as effective as I thought it was going to be especially for the price of the serum, but I saw a difference in my skin within the first couple days of using it. That’s never happened before, even with other high-end serums. I would love to purchase this again the website has another sale!"

— Rozi (5/5)

Epic product, improved skin barrier, odd dispenser

"Of all the Diamond products this one is probably the game changer. Morning and evening I have seen measurable improvement in my skin barrier and tightness. It’s literally a miracle serum. I can’t “feel” it working but the results are so obvious. This is the one! My only negative feedback is that the dispenser is so odd. I do have larger hands but I can’t imagine small hands even being able to get this to pump easily. Random egg shape and sometimes hard to get all the product out. It’s a small volume for a product that is recommended for morning and night, unlike the easy to dispense, larger volume or the emulsion."

— Preston J. (4/5)

Noticeable results

"I have just started using the Instafacial Infusion and after 1 application there are noticeable differences."

— Geri B. (5/5)

Great for elasticity

"I have noticed a big difference in my skin’s overall appearance after using the infusion. The lower half of my face feels tightened and more sculpted."

— Jordyn (5/5)

Morning and night

"I love this product. Texture and overall performance. Leave my skin hydrated but not greasy. Improves the appearance of fine lines."

— Laura (5/5)

Luxury Skincare That Actually Performs

"Dr. Diamond’s Metacine Infusion has completely elevated my skincare routine. The texture is incredibly elegant and silky, and it instantly makes my skin feel hydrated, calm, and revitalized. What I noticed most was how much smoother and firmer my skin started looking after consistent use. It layers perfectly with Plasma and the rest of the Metacine line, helping everything absorb beautifully while giving my skin a healthy, refined glow. My complexion looks brighter, more even, and noticeably more refreshed every morning. Fine lines appear softened and my skin feels deeply nourished without ever feeling heavy. This product truly gives that luxury in-office facial look at home. If you want radiant, healthy looking skin with a high end formulation that delivers visible results, Infusion is exceptional."

— Alberto (5/5)

My new favorite

"After being happy with another skin care line for many years I finally tried Dr. Diamond’s products. I didn’t want to switch, but I have to say that the results were so great that I have added them to my routine. I’m thinking they will end up replacing the older line altogether. My skin is plumper, more hydrated, and smoother. At 57 I have more confidence in a no-makeup look."

— Tamineh A. (5/5)

Too early to tell effects,

"Too early to tell effects, but like it so far."

— Christina (4/5)

Q&A