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INSTAFACIAL® COLLECTION DUO

InstaFacial® Plasma + Emulsion

Key Benefits

  • Repair & Rejuvenate: supports skin’s natural renewal processes for healthier, more youthful-looking skin
  • Brightening: reduces appearance of hyperpigmentation for a brighter complexion
  • Firmness: supports collagen production for firmer & more lifted skin
  • Resurface & Renew: bioactive retinoid gently resurfaces to improve the look of uneven tone & texture
  • Non-irritating: next-generation, direct-acting retinoid delivers potent results with less irritation than traditional retinoids
  • Non-greasy finish that absorbs seamlessly & layers beautifully under makeup
  • Vegan & Fragrance-Free: designed for all skin types, including sensitive skin

Description

Inspired Dr. Diamond's signature InstaFacial®, Plasma + Emulsion work synergistically to support healthier, more youthful-looking skin. Plasma is inspired by the platelet-rich plasma (PRP) step of the treatment, leveraging bioengineered growth factors & signaling peptides to support cellular communication & skin repair. Emulsion is inspired by the gentle laser & microneedling steps, combining a next-generation retinoid with advanced hydration technology to support renewal, resurfacing & improving texture & refine tone. Together, they target both the surface & deeper layers of skin to help improve the appearance of fine lines & wrinkles, texture, radiance & overall skin health.

Key Ingredients

  • Five Different Types of Bioengineered Growth Factors in Plasma: supports cellular renewal, healing & collagen, elastin & hyaluronic acid production
  • Copper Tripeptide-1 in Plasma: naturally found in human plasma, stimulates skin renewal & fades hyperpigmentation & sun damage over time for brighter complexion
  • Botox-like Peptide (Acetyl Hexapeptide-8) in Plasma: relaxes facial muscles, reducing appearance of fine lines & wrinkles
  • Hydroxypinacolone Retinoate (HPR) in Emulsion: a next generation, bioactive, direct acting retinoid that resurfaces & renews without metabolic conversion, making it gentler on skin while maintaining potency
  • Myristoyl Nonapeptide-3 in Emulsion: a biomimetic, anti-aging peptide designed to mimic the effects of retinoic acid to support cell turnover & collagen production without irritation

View Full List

PLASMA
O WATER ● GLYCERIN O 1,2-HEXANEDIOL ● NICOTIANA BENTHAMIANA HEXA-PEPTIDE-40 SH-OLIGOPEPTIDE-1 ● N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE ● SH-OLIGOPEPTIDE-1 ● SH-OLIGOPEPTIDE-2 ● SH-POLYPEPTIDE-1 ● SH-POLYPEPTIDE-11 ● SH-POLYPEPTIDE-9 ● ACETYL HEXAPEPTIDE-8 ● ACETYL GLUTAMINE ● COPPER TRIPEPTIDE-1 ● RAPHANUS SATIVUS (RADISH) ROOT EXTRACT ● BACILLUS/FOLIC ACID FERMENT FILTRATE EXTRACT O HYDROXYACETO-PHENONE O DISODIUM ACETYL GLUCOSAMINE PHOSPHATE O SODIUM GLUCURONATE ● SODIUM HYALURONATE O SODIUM PHYTATE O MAGNESIUM SULFATE O HYDROXYETHYL-CELLULOSE O LECITHIN OCITRIC ACID O MALTODEXTRIN O PROPANEDIOL ● BUTYLENE GLYCOL O PENTYLENE GLYCOL O ETHYLHEXYLGLYCERIN ● CAPRYLYL GLYCOL O PHENOXYETHANOL

EMULSION
O WATER O DIMETHICONE ● GLYCERIN O BUTYLENE GLYCOL O DIMETHICONE CROSSPOLYMER ● NIACINAMIDE O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER O MACADAMIA INTEGRIFOLIA SEED OIL ● NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-OLIGOPEPTIDE-1 ● MYRISTOYL NONAPEPTIDE-3 ● PALMITOYL TETRAPEPTIDE-7 ● PALMITOYL TRIPEPTIDE-38 O CAMELLIA SINENSIS LEAF EXTRACT O DIMETHICONE/PEG-10/15 CROSSPOLYMER ● SODIUM HYALURONATE CROSSPOLYMER ● SODIUM ACETYLATED HYALURONATE ● HYDROLYZED SODIUM HYALURONATE ● SODIUM HYALURONATE ● HYDROXYPINACOLONE RETINOATE ● TOCOPHERYL ACETATE O PHOSPHOLIPIDS O SODIUM PHYTATE ● SQUALANE ● CYCLIC LYSOPHOSPHATIDIC ACID ● SODIUM CARBOXYMETHYL BETA-GLUCAN ● GLYCYRRHETINIC ACID O LECITHIN O DIMETHICONOL O CITRIC ACID O HYDROXYPROPYL CYCLODEXTRIN O DIMETHYL ISOSORBIDE O PENTYLENE GLYCOL O CAPRYLYL GLYCOL O ETHYLHEXYLGLYCERIN O CHLORPHENESIN O POLYSORBATE 60 O PHENOXYETHANOL

How to Use

AM After cleansing, gently press 2-3 drops of Plasma on face, neck & décolleté.

PM Apply Plasma as instructed in the AM. After, use 1 pump of Emulsion & apply thin layer to face, neck & décolleté.

Optimal Results: AM + PM follow Plasma with 1-2 pumps of Infusion on slightly damp skin. Finish with HYDR/O to seal in actives.

Pairs well with

CLINICALLY PROVEN.
BACKED BY SCIENCE.

Independent clinical study of 35 participants representing all skin types on the Fitzpatrick scale. Clinical evaluations were conducted after 4 & 8 weeks of using InstaFacial® Plasma + Emulsion. Before & Afters shown at 8 weeks.

  • 94% had improvement in crow’s feet lines after 8 weeks.1
  • 91% reported their skin looked firmer & lifted after 8 weeks.2
  • 91% reported smoother & more refined skin texture after 4 weeks.2
  • 83% reported healthier looking & more youthful skin after 4 weeks.2
  • 83% reported skin looked more luminous & radiant after 8 weeks.2

INFORMED BY MEDICINE. MADE WITH TECHNOLOGY.

  • CLINICAL TWO STEP

    The InstaFacial® Duo brings together two of the most transformative steps from Dr. Diamond's signature InstaFacial® treatment. Plasma is inspired by platelet-rich plasma (PRP), rich in growth factors that support the skin's natural repair processes. Emulsion is inspired by the treatment's laser resurfacing component, helping accelerate cellular renewal while improving texture, tone & overall skin quality. Together, they translate the principles of regenerative aesthetics into a comprehensive at-home rejuvenation routine.

  • REPAIR MEETS RENEWAL

    Healthy, youthful-looking skin depends on both effective cellular communication & continuous renewal. Over time, the biological signals responsible for repair begin to decline while cellular turnover slows, contributing to visible signs of aging. Plasma supports the skin's natural repair processes through bioengineered growth factors & signaling peptides, while Emulsion combines a direct-acting retinoid with a growth factor, an advanced hyaluronic acid complex & niacinamide to support cellular renewal & resurfacing. Together, they address two of the most important pathways involved in maintaining healthy skin function.

  • DUAL ACTION

    Growth factors & retinoids work through different yet complementary mechanisms. Growth factors help support cellular communication pathways involved in repair, collagen production & skin rejuvenation. Retinoids help accelerate cellular turnover & support the emergence of healthier, younger-looking skin. By pairing five different types of bioengineered, human-identical growth factors with Hydroxypinacolone Retinoate (HPR), a next-generation direct-acting retinoid, the InstaFacial® Duo helps support firmer, smoother, brighter & more resilient-looking skin.

  • MOLECULAR SYNERGY

    The InstaFacial® Duo is built upon the principle of Molecular Synergy. Plasma helps support the biological signals responsible for repair & rejuvenation, while Emulsion helps optimize cellular renewal & resurfacing. Advanced signaling peptides, growth factors, hyaluronic acid, niacinamide & direct-acting retinoid technology work together to support multiple pathways involved in skin rejuvenation simultaneously. The result is a comprehensive system designed to visibly improve firmness, texture, tone, radiance & overall skin quality with continued use.

ENGINEERED FOR REPAIR & RENEWAL.

See The Science
  • CELLULAR COMMUNICATION

    Inspired by the regenerative properties of platelet-rich plasma (PRP), InstaFacial® Plasma features five different types of bioengineered, human-identical growth factors that support cellular communication, collagen production, nutrient delivery & skin renewal to reduce the appearance of fine lines & wrinkles & promote a firmer, healthier-looking complexion.

  • RESURFACE & RENEW

    These two ingredients were intentionally paired in InstaFacial® Emulsion to support skin renewal through different yet complementary mechanisms. HPR supports cellular turnover by directly binding with retinoid receptors without metabolic conversion, which traditional retinoids go through. By bypassing this pathway, HPR supports renewal without the side effects of peeling & irritation.

    Myristoyl Nonapeptide-3 reinforces rejuvenation pathways through peptide signaling & by working with HPR, the two ingredients create a more comprehensive approach to visible skin renewal.

  • BARRIER OPTIMIZATION

    Niacinamide is a multi-functional Vitamin B3 that strengthens the skin barrier, improves the appearance of uneven tone & texture & supports a smoother, brighter, more resilient complexion. In InstaFacial® Emulsion, niacinamide works synergistically with HPR, Niacinamide supports skin renewal wile strengthening the barrier without sensitizing the barrier.

  • ZERO COMPROMISE

    Hydration & barrier integrity play a critical role in skin rejuvenation. A complex of four molecular weights of hyaluronic acid, combined with niacinamide, lipopeptides & squalane, helps replenish moisture, strengthen the barrier & support skin resilience. A strong barrier is the foundation that creates the optimal conditions for cellular renewal, repair & collagen production.

See The Science

A ROUTINE ENGINEERED FOR RESULTS.

INSTAFACIAL® PLASMA

Bioactive Growth Factor Serum

A serum inspired by platelet-rich plasma (PRP), a key modality in the Diamond InstaFacial®, featuring five different types of bioengineered, human-identical growth factors, signaling peptides & hyaluronic acid to support the skin's natural repair & rejuvenation.

HOW TO USE: After cleansing, gently press 2-3 drops on slightly damp skin. Apply on face, neck & décolleté.

Frequently Asked Questions

Why are Plasma + Emulsion paired together?

Plasma + Emulsion were designed to work synergistically. Plasma helps support cellular communication & repair through bioengineered growth factors & signaling peptides, while Emulsion supports cellular renewal through direct-acting retinoid technology. Together, they address multiple pathways involved in visible skin rejuvenation.

What inspired the InstaFacial® Duo?

The Duo is inspired by two key steps of Dr. Diamond's signature InstaFacial® treatment. Plasma is inspired by platelet-rich plasma (PRP), while Emulsion is inspired by the laser resurfacing component of the procedure. Together, they bring the principles of regenerative aesthetics into an at-home routine.

Is Emulsion a moisturizer?

No, Emulsion provides significant hydration & barrier support, but it is first & foremost a rejuvenation treatment. For additional hydration & barrier fortification, pair Emulsion with HYDR/O.

Can I use the InstaFacial® Duo every day?

Plasma is suitable for daily morning & evening use. Emulsion is designed for nightly use. If you are new to retinoids, begin using Emulsion 2–3 nights per week & gradually increase frequency as tolerated.

Can I use the InstaFacial® Duo after a cosmetic procedure?

Plasma may be incorporated into many post-procedure routines to support the skin's natural repair processes. Because Emulsion contains a bioactive retinoid, we recommend discontinuing use approximately 10 days prior to a procedure & waiting until the skin has sufficiently healed, typically about 10 days post-procedure, before reintroducing it into your routine. Because every procedure & recovery timeline is different, we recommend consulting your physician regarding when to resume skincare products following treatment.

Can I use the InstaFacial® Duo with Vitamin C or exfoliating acids?

Yes, most users can incorporate the Duo into routines containing Vitamin C & exfoliating acids. For Vitamin C with high concentration L-Ascorbic Acid (15-20%), we recommend using Plasma first, waiting 15-20 minutes, then applying Vitamin C; alternatively we recommend alternating AM/PM use of Plasma & Vitamin C.

Is the InstaFacial® Duo suitable for sensitive skin?

Yes, Plasma was formulated for daily use & Emulsion combines a direct-acting retinoid with growth factors, peptides & advanced hydration technology designed to support skin comfort throughout the renewal process.

Is it OK to wear the InstaFacial® Duo under my makeup?

Yes, absolutely. The products layer beautifully & provide the perfect canvas for makeup.

COMPLETE THE ROUTINE

Overall rating: 4.7714286 / 5 from 245 reviews.

AI Generated Review Summary

The INSTAFACIAL® COLLECTION DUO is praised for its rejuvenating effects, with customers noting significant improvements in skin appearance, hydration, and radiance. The product's results are highly acclaimed, with many customers reporting a noticeable difference and a desire to repurchase. The packaging is also appreciated for its elegance and functionality.

Summary topics

  • skin appearance: 11%
  • product results: 19%
  • fine lines improvement: 8%
  • skin feel: 15%
  • product packaging: 9%

Review topics: [size, color, absorbs, scent, irritation, results, improvement, price, wrinkles, weight, quality, works, feels, benefits, ingredients, lines, texture, skin, packaging, use, spots, looks, bottle, difference, glow, face, effects, skincare, pores, appearance].

Review highlights

  • "Love these products - how the feel and the results (smoother texture and appearance)."Alex
  • "My skin feels so soft and looks a lot healthier and radiant."Adrianab119
  • "The bioactive retinoids have made her skin look so much younger and have erased fine lines."Jenjenjennn

Reviews

Amazing products!

"I’ve been using this duo since April and have seen results in my face right away. Definitely worth the investment!"

Jenna (5/5)

The absolute best hands down!

"These products truly give wonderful results in a week or two. Throw away everything and stop buying into internet lies. I reluctantly tried this due to its price point and because I’ve spent so much on other skincare regimens that have been incredibly expensive and disappointing. I am streamlining to just these products for the moment. I’m in my 60’s and have tried a ridiculous number of protocols. Drawers of disappointing products! This is the one that has truly worked for me. Thank you Dr Diamond!"

Mary H. (5/5)

So good!

"I’ve been using this line for a year or so and it’s perfect. It has streamlined my routine. I’m not sure it’s reversed any lines but it’s definitely slowed new ones!"

Bridget (5/5)

Love The Pair

"I haven't used these products long enough for results, but they are exceptional in formula and application. As a long time user of retinols, I love the gel like consistency of the Interfacial Emulsion. The Interfacial Serum is a hit. It sinks right in and no sticky residue. A little goes a long way with both these products."

Bev (5/5)

"I love these products, they really work. My skin has never looked better. They are expensive though."

karen (5/5)

Best on the market. Well worth the cost.

"I always say you can’t put a price on good skin. I found this product about two years ago and I’ve used it ever since. My skin has never been clearer, smoother, tighter or had more glow to it. I get asked all the time if it’s worth it. What would you pay to look this good is my response."

Tanya S. (5/5)

"Love this product so very much… Wish it was cheaper!"

Sarah (5/5)

perfect combo

"I was already using 2 of the products and decided to try the plasma. So happy I did because it compliments my whole skin care routine. I was already seeing results by using 2 of the products and now I;m even more impressed by the plasma addition"

Kelli P. (5/5)

Love!!

"These products have changed my skin. I love the way they feel and leave my skin feeling all day. Within a week of using my husband told me I was just looking so beautiful and glowing. Nothing else in my routine had changed. My skin has never looked this good! I bought the discovery set and have now purchased the full bottles."

Anna (5/5)

A retinoid that my sensitive skin can tolerate!

"I've been using for a couple weeks and notice a difference - I was surprised to receive compliments on how bright and even my skin looks after using it for such a short time. I plan to repurchase and looking forward to seeing long term results!"

CJ (5/5)

Q&A