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Translation missing: en.Plasma + HYDR/O Duo
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Plasma + HYDR/O Duo

The Bioactive Duo for Holiday Radiance.

Key Benefits
  • Repair & Rejuvenate: supports skin’s natural renewal processes for healthier, more youthful-looking skin
  • Brightening: reduces appearance of hyperpigmentation for a brighter complexion
  • Anti-aging: reduces the appearance of fine lines & wrinkles
  • Hydrate & Protect: delivers immediate, multi-layer hydration for healthier-looking skin
  • Barrier Repair & Protection: strengthens & fortifies the skin barrier while reducing transepidermal water loss to maintain optimal moisture levels
  • Tone & Texture: reduces the appearance of redness & improves overall skin texture, softness & elasticity
  • Non-greasy finish that absorbs seamlessly & layers beautifully under makeup
  • Vegan & Fragrance-Free: designed for all skin types, including sensitive skin

Description

The Bioactive Duo for holiday radiance. A two-step recovery routine that helps strengthen the skin barrier, replenish moisture & support visible barrier repair. Plasma & HYDR/O are paired to deliver biomimetic repair & advanced hydration to help restore balance & protect against daily environmental stressors.

InstaFacial® Plasma 30ml:
A weightless serum inspired by platelet-rich plasma (PRP). Formulated with five different types of bioengineered, human identical growth factors, signaling pepties & hyaluronic acid to repair & rejuvenate skin on a cellular level.

HYDR/O 50gm:
A next-generation bioactivated moisturizer powered by proprietary Bioactive Hydrolipid Fusion™ to deeply hydrate, strengthen the skin barrier, support the microbiome & defend against environmental stressors.

Key Ingredients
  • Five Different Types of Bioengineered Growth Factors in Plasma: supports cellular renewal, healing & collagen, elastin & hyaluronic acid production
  • Botox-like Peptide (Acetyl Hexapeptide-8) in Plasma: relaxes facial muscles, reducing appearance of fine lines & wrinkles
  • N-Prolyl Palmitoyl Tripeptide-56 Acetate in Plasma: advanced lipopeptide that supports fibroblast to increase collagen production, visibly improving firmness, smoothness & the appearance of wrinkles
  • Bioactive Hydrolipid Fusion™ in HYDR/O: proprietary & patent pending blend of 27 biomimetic micro-molecules that supports hydration, barrier repair & skin resilience
  • Hydro HA-7 in HYDR/O: a network of seven multi-weight molecules of hyaluronic acid that deliver multi-depth hydration

View Full List

PLASMA
O WATER ● GLYCERIN O 1,2-HEXANEDIOL ● NICOTIANA BENTHAMIANA HEXA-PEPTIDE-40 SH-OLIGOPEPTIDE-1 ● N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE ● SH-OLIGOPEPTIDE-1 ● SH-OLIGOPEPTIDE-2 ● SH-POLYPEPTIDE-1 ● SH-POLYPEPTIDE-11 ● SH-POLYPEPTIDE-9 ● ACETYL HEXAPEPTIDE-8 ● ACETYL GLUTAMINE ● COPPER TRIPEPTIDE-1 ● RAPHANUS SATIVUS (RADISH) ROOT EXTRACT ● BACILLUS/FOLIC ACID FERMENT FILTRATE EXTRACT O HYDROXYACETO-PHENONE O DISODIUM ACETYL GLUCOSAMINE PHOSPHATE O SODIUM GLUCURONATE ● SODIUM HYALURONATE O SODIUM PHYTATE O MAGNESIUM SULFATE O HYDROXYETHYL-CELLULOSE O LECITHIN OCITRIC ACID O MALTODEXTRIN O PROPANEDIOL ● BUTYLENE GLYCOL O PENTYLENE GLYCOL O ETHYLHEXYLGLYCERIN ● CAPRYLYL GLYCOL O PHENOXYETHANOL

HYDR/O
O WATER (AQUA) O OCTYLDODECANOL O GLYCERYL STEARATE ● GLYCERIN O DICAPRYLYL CARBONATE ● BUTYROSPERMUM PARKII (SHEA) BUTTER ● SQUALANE ● NIACINAMIDE O POLYGLYCERYL-2 STEARATE O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER ● FRUCTOOLIGOSACCHARIDES O PENTYLENE GLYCOL ● SODIUM HYALURONATE ● SODIUM ACETYLATED HYALURONATE ● SODIUM HYALURONATE CROSSPOLYMER ● HYDROXYPROPYLTRIMONIUM HYALURONATE ● HYALURONIC ACID ● C12-13 ALKYL GLYCERYL HYDROLYZED HYALURONATE ● HYDROLYZED SODIUM HYALURONATE ● PHYTOSPHINGOSINE ● CERAMIDE AP ● CERAMIDE NP ● CERAMIDE NS ● CERAMIDE AS ● CERAMIDE EOP ● LINOLEIC ACID ● LINOLENIC ACID ● PHYTOSTEROLS ● ALEURITES MOLUCCANUS SEED OIL ● PLUKENETIA VOLUBILIS SEED OIL ● TRIOLEIN ● PHOSPHOLIPIDS ● PROPANEDIOL ● POLYGLYCERYL-6 RICINOLEATE ● POLYGLYCERYL-6 CAPRYLATE ● POLYGLYCERYL-4 CAPRATE ● POLYGLYCERYL-3 COCOATE ● TOCOPHEROL ● CHOLESTEROL ● PALMITIC ACID ● OLEIC ACID ● STEARIC ACID ● GLYCERYL DIOLEATE ● HYDROGENATED LECITHIN ● 2,3-BUTANEDIOL ● PCA ● SODIUM LAUROYL LACTYLATE O SODIUM PHYTATE O  XANTHAN GUM ● BETA VULGARIS (BEET) ROOT EXTRACT O STEARYL ALCOHOL O ETHYLHEXYLGLYCERIN O CARBOMER O PHENOXYETHANOL O CAPRYLYL GLYCOL O HEXYLENE GLYCOL

How to Use

AM + PM After cleansing, gently press 2-3 drops of Plasma on damp skin. Apply on face, neck & décolleté. For HYDR/O, using the spatula, apply a generous amount to the face, neck & décolleté.

Optimal results: Immediately following Plasma, apply Infusion before HYDR/O in the AM. In PM, Emulsion can be added after Plasma + Infusion & before HYDR/O. EyeLift can be added after Plasma if desired in AM + PM.

Pairs well with

Translation missing: en.EyeLift

EyeLift

2 sizes
$50 - $225
Translation missing: en.INSTAFACIAL® EMULSION

INSTAFACIAL® EMULSION

3 sizes
$40 - $350
Translation missing: en.INSTAFACIAL® INFUSION

INSTAFACIAL® INFUSION

2 sizes
$50 - $325
Translation missing: en.INSTAFACIAL® COLLECTION TRIO

INSTAFACIAL® COLLECTION TRIO

2 size
$125 - $875
Translation missing: en.INSTAFACIAL® COLLECTION DUO

INSTAFACIAL® COLLECTION DUO

2 sizes
$75 - $550
Translation missing: en.INSTAFACIAL® TRIO DISCOVERY SET

INSTAFACIAL® TRIO DISCOVERY SET

1 size
$125

CLINICALLY PROVEN.
BACKED BY SCIENCE.

Before & Afters:

  • Plasma + Emulsion: shown at 8 weeks
  • HYDR/O: shown at 4 weeks
  • 94% had improvement in crow’s feet lines after 8 weeks.1
  • 91% reported their skin looked firmer & lifted after 8 weeks.2
  • 91% reported smoother & more refined skin texture after 4 weeks.2
  • 83% reported healthier looking & more youthful skin after 4 weeks.2
  • 83% reported skin looked more luminous & radiant after 8 weeks.2

Forehead Wrinkles

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Brightness & Hyperpigmentation

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Fine Lines - Crow's Feet

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Fine Lines - Crow's Feet

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Your New 5 Minute Routine

INSTAFACIAL® PLASMA

Bioactive Growth Factor Serum

A serum inspired by platelet-rich plasma (PRP), a key modality in the Diamond InstaFacial®, featuring five different types of bioengineered, human-identical growth factors, signaling peptides & hyaluronic acid to support the skin's natural repair & rejuvenation.

HOW TO USE: After cleansing, gently press 2-3 drops on slightly damp skin. Apply on face, neck & décolleté.

Learn More

Frequently Asked Questions

See All Faqs

How do I layer Plasma with other Metacine products?

Apply Plasma first, followed by Infusion, EyeLift, Emulsion (evening) & HYDR/O as the final step to seal in hydration.

Is Plasma the same as PRP?

No, Plasma is inspired by PRP, but it is not blood-derived. It uses bioengineered, human-identical growth factors designed to mimic the regenerative properties found in PRP.

Are Dr. Diamond’s Metacine products suitable for sensitive skin?

Yes. All products are designed to be lightweight, non-irritating & suitable for daily use. As with any active skincare product, start gradually if your skin is sensitive to allow time to acclimate.

Can I use Plasma with retinoids, Vitamin C or exfoliating acids?

Yes. Plasma can be incorporated into routines that include retinoids, Vitamin C & exfoliating acids. For retinoids, apply Plasma first, followed by your retinoid treatment. For Vitamin C, Plasma can be used alongside most Vitamin C formulas. If using a high concentration of pure L-Ascorbic Acid (10–20%), we recommend applying Plasma first & allowing it to absorb before applying Vitamin C, or alternating use between morning & evening. For exfoliating acids, apply your exfoliating treatment after cleansing, then follow with Plasma to support hydration & skin recovery.

Why is Plasma red?

Plasma's color comes from naturally derived radish root extract in the formula & may vary slightly from batch to batch. This color variation is normal & does not affect product efficacy.

Is it OK to wear Dr. Diamond’s Metacine products under my makeup?

Yes, absolutely. The products layer beautifully & provide the perfect canvas for makeup.

Is HYDR/O suitable for sensitive skin?

Yes. HYDR/O was formulated to support sensitive skin. Its biomimetic lipids, ceramides & hydration technologies help strengthen the skin barrier while promoting comfort & resilience.

When should I use HYDR/O?

HYDR/O can be used morning & evening as the final step in your skincare routine. Apply after serums & treatments to help lock in hydration & support barrier function. We recommend using SPF after HYDR/O in the mornings.

Can I use HYDR/O with Plasma, Infusion, Emulsion, or EyeLift?

Yes. HYDR/O was designed to complement the entire Metacine collection. It helps seal in the benefits of previously applied treatments while supporting hydration, barrier integrity & skin resilience.

Can I use these products after a cosmetic procedure?

Because every procedure & recovery timeline is different, we recommend following your physician's post-treatment instructions regarding when to resume skincare products.

See All Faqs

COMPLETE THE ROUTINE

Overall rating: 5.0 / 5 from 4 reviews.

AI Generated Review Summary

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Review highlights

Reviews

Finally a product that works!!

"I absolutely love Instafacial Plasma! I've been using it every day on my face and neck for almost a month, and I'm already seeing a noticeable difference. My skin looks healthier, smoother, and more refreshed, and I'm excited to see how much more it improves after 8 weeks of treatment—and beyond!"

— Natasha (5/5)

Beyond expectations

"I’m on 7th floor and couldn’t believe improvement in less than 7 days. Small dry patches disappeared redness reduced. Even echo lines that were former dimples improved. Will confess I did also use cream with the red spoon that sits on top. Love packaging too❣️"

— NG (5/5)

Can’t live without!

"I have been using the Metacine line for 2 weeks. The change in my skin is the difference between night and day. More hydrated, plump, pores are minimized and skin is smooth. I am so grateful I found this growth factor serum and the entire Metacine line."

— Ronnie (5/5)

"love this product"

— Linda (5/5)

Q&A