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Translation missing: en.HYDR/O

HYDR/O

Bioactive Hydrolipid Barrier Moisturizer

Key Benefits
  • Hydrate & Protect: delivers immediate, multi-layer hydration for healthier-looking skin
  • Barrier Repair: strengthens & fortifies the skin barrier while reducing transepidermal water loss to maintain optimal moisture levels
  • Protection & Defense: balances the skin microbiome & protects against environmental stressors & irritants
  • Tone & Texture: reduces the appearance of redness & improves overall skin texture, softness & elasticity
  • Non-greasy finish that absorbs seamlessly & layers beautifully under makeup
  • Vegan & Fragrance-Free: designed for all skin types, including sensitive skin

Description

Instant hydration in just one use. A next generation bioactivate moisturizer that deeply hydrates, repairs & fortifies skin's barrier from cell to surface. Powered by proprietary & patent-pending Bioactive Hydrolipid Fusion™, a biomimetic fusion of skin identical lipids & water synthesized through sonication to form uniform nano-molecules for rapid absorption, HYDR/O uniquely mimics youthful skin’s ability to self-hydrate, balancing the microbiome & protecting against external irritants & pathogens.

Key Ingredients
  • Bioactive Hydrolipid Fusion™: proprietary & patent pending blend of 27 biomimetic micro-molecular active ingredients that supports hydration, barrier repair & skin resilience
  • Hydro HA-7: a network of seven multi-weight molecules of hyaluronic acid that deliver multi-depth hydration
  • Biomimetic Natural Moisture Factors: containing glycerin, PCA, amino acid derivatives & more along with other humectants like beet root extract, which boosts skin's Natural Moisturizing Factors
  • Skin-identical lipids: essential fatty acids such as linoleic, linolenic & phyto-cholesterol work synergistically to fortify internal skin lipids to prevent water loss & strengthen skin’s barrier

View Full List

O WATER (AQUA) O OCTYLDODECANOL O GLYCERYL STEARATE ● GLYCERIN O DICAPRYLYL CARBONATE ● BUTYROSPERMUM PARKII (SHEA) BUTTER ● SQUALANE ● NIACINAMIDE O POLYGLYCERYL-2 STEARATE O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER ● FRUCTOOLIGOSACCHARIDES O PENTYLENE GLYCOL ● SODIUM HYALURONATE ● SODIUM ACETYLATED HYALURONATE ● SODIUM HYALURONATE CROSSPOLYMER ● HYDROXYPROPYLTRIMONIUM HYALURONATE ● HYALURONIC ACID ● C12-13 ALKYL GLYCERYL HYDROLYZED HYALURONATE ● HYDROLYZED SODIUM HYALURONATE ● PHYTOSPHINGOSINE ● CERAMIDE AP ● CERAMIDE NP ● CERAMIDE NS ● CERAMIDE AS ● CERAMIDE EOP ● LINOLEIC ACID ● LINOLENIC ACID ● PHYTOSTEROLS ● ALEURITES MOLUCCANUS SEED OIL ● PLUKENETIA VOLUBILIS SEED OIL ● TRIOLEIN ● PHOSPHOLIPIDS ● PROPANEDIOL ● POLYGLYCERYL-6 RICINOLEATE ● POLYGLYCERYL-6 CAPRYLATE ● POLYGLYCERYL-4 CAPRATE ● POLYGLYCERYL-3 COCOATE ● TOCOPHEROL ● CHOLESTEROL ● PALMITIC ACID ● OLEIC ACID ● STEARIC ACID ● GLYCERYL DIOLEATE ● HYDROGENATED LECITHIN ● 2,3-BUTANEDIOL ● PCA ● SODIUM LAUROYL LACTYLATE O SODIUM PHYTATE O  XANTHAN GUM ● BETA VULGARIS (BEET) ROOT EXTRACT O STEARYL ALCOHOL O ETHYLHEXYLGLYCERIN O CARBOMER O PHENOXYETHANOL O CAPRYLYL GLYCOL O HEXYLENE GLYCOL

How to Use

AM + PM Using the spatula, apply a generous amount to the face, neck & décolleté.

Optimal Results: Use as the final step in your routine after the InstaFacial® Collection to seal in actives.

Discovery size products are final sale & non-returnable.

Pair with well

Translation missing: en.INSTAFACIAL® PLASMA

INSTAFACIAL® PLASMA

3 sizes
$35 - $200
Translation missing: en.EyeLift

EyeLift

2 sizes
$50 - $225
Translation missing: en.INSTAFACIAL® EMULSION

INSTAFACIAL® EMULSION

3 sizes
$50 - $350
Translation missing: en.INSTAFACIAL® INFUSION

INSTAFACIAL® INFUSION

2 sizes
$40 - $325
Translation missing: en.INSTAFACIAL® COLLECTION DUO

INSTAFACIAL® COLLECTION DUO

2 sizes
$85 - $550
Translation missing: en.INSTAFACIAL® COLLECTION TRIO

INSTAFACIAL® COLLECTION TRIO

1 size
$875
Translation missing: en.INSTAFACIAL® TRIO DISCOVERY SET

INSTAFACIAL® TRIO DISCOVERY SET

1 size
$125

CLINICALLY PROVEN.
BACKED BY SCIENCE.

Independent clinical study of 32 participants representing all skin types on the Fitzpatrick scale. Clinical evaluations were conducted immediately, after 24 hours & at 1, 2, & 4 weeks of using HYDR/O.

Before & Afters shown at 4 weeks.

  • 100% of participants showed improvement in barrier strength indicating a decrease in TEWL after 1, 2 & 4 weeks, measured by tape stripping.7
  • 93% reported their skin felt less dry & tight after 1 week.8
  • 84% reported their skin looked plump & firm after 1 week.8
  • 90% reported HYDR/O had relieved their dry skin after 4 weeks.8
  • 90% reported that this was the best their skin had looked in a long time after 4 weeks.8

Redness

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Luminosity & Smoothness

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Redness

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Texture

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Texture

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INFORMED BY MEDICINE. MADE WITH TECHNOLOGY.

  • SONICATION TECHNOLOGY

    Proprietary & patent-pending Bioactive Hydrolipid Fusion™ is the breakthrough hydration technology behind HYDR/O. While water & oil won’t naturally mix, through sonication, high-energy sound waves fuse biomimetic lipids such as essential fatty acids, ceramides, cholesterol & phospholipids with water to form a uniform & stable colloid that creates micromolecules which can be rapidly absorbed into skin rather than sitting on skin surface. The result is unprecedented hydration & barrier fortification.

  • BARRIER BREAKDOWN

    The skin barrier, known as the stratum corneum, is the body's first line of defense. Composed of skin cells, natural moisturizing factors (NMFs) & essential lipids including ceramides, cholesterol & fatty acids, its primary function is to retain moisture while protecting against pathogens, irritants & environmental stressors. As skin ages, its ability to maintain & regulate this protective barrier begins to decline. This can lead to increased transepidermal water loss (TEWL), dehydration, sensitivity & visible signs of aging, leaving skin thinner, drier, weaker & less resilient over time.

  • A HEALTHY MICROBIOME

    A healthy balance of lipids is essential for maintaining hydration, barrier integrity & a thriving microbiome. HYDR/O helps activate the skin's natural hydration regulation by replenishing skin-identical lipids & attracting moisture through natural moisturizing factors (NMFs) & 7 multi-weights of hyaluronic acid. By supporting a healthy microbiome & reinforcing barrier function, HYDR/O strengthens the skin's natural defenses against irritants, pathogens & environmental stressors while promoting healthier, more resilient-looking skin.

  • MOLECULAR SYNERGY

    HYDR/O approaches hydration from every angle. Featuring an arsenal of hydration protection including Bioactive Hydrolipid Fusion™, Hydro-HA-7, biomimetic humectants & synergistic skin identical lipids, together, these molecules attract, lock in & retain, reducing trans-epidermal water loss (TEWL) & reinforcing the barrier to moisturize dry skin for smoother, more supple & plumper looking skin.

Paraben Free

Cruelty Free

Sulfate Free

Science Driven

HYDRATION, ACTIVATED.

See The Science
  • BREAKTHROUGH IN HYDRATION

    A patent-pending biomimetic colloid, Bioactive Hydrolipid Fusion™ is created through sonication technology, where high-energy sound waves transform lipids & water into a highly uniform system of 27 skin-identical micro-molecules, including ceramides, essential fatty acids & plant-based cholesterol. Sonication technology fuses water & lipids & turns them into nano-molecules that can be rapidlt absorbed into skin instead of sitting on the surface of skin & trapping moisture. Designed to mimic the skin's natural hydrolipid structure, this advanced hydration technology replenishes barrier lipids, improves moisture retention & supports healthier, more resilient-looking skin.

  • MULTI-LAYER HYDRATION

    Hydro-HA 7 is a network of seven different weights of hyaluronic acid to help attract, bind & retain moisture at varying depths of skin while reducing trans-epidermal water loss (TEWL). The result is immediate & long-lasting hydration for smoother, plumper, more supple-looking skin.

  • LOCK IN MOISTURE

    Healthy skin depends on its ability to attract, regulate & retain moisture. HYDR/O combines biomimetic humectants, natural moisturizing factors & barrier-supporting lipids to support the skin's natural hydration regulation. Together, these technologies deliver multi-layer hydration, help seal in the benefits of previously applied treatments & strengthen the skin's defenses against irritants, pathogens & environmental stressors.

  • HYDROLIPID RESTORATION

    As skin ages, lipid production declines, weakening the hydrolipid barrier, making skin more prone to dehydration. Linoleic Acid, Linolenic Acid, Ceramides & Phyto-Cholesterol in HYDR/O replenish skin-identical lipids to strengthen the barrier, reduce moisture loss & support long-lasting hydration & a strong hydrolipid barrier.

See The Science

A ROUTINE ENGINEERED FOR RESULTS.

INSTAFACIAL® PLASMA

Bioactive Growth Factor Serum

A serum inspired by platelet-rich plasma (PRP), a key modality in the Diamond InstaFacial®, featuring five different types of bioengineered, human-identical growth factors, signaling peptides & hyaluronic acid to support the skin's natural repair & rejuvenation.

HOW TO USE: After cleansing, gently press 2-3 drops on slightly damp skin. Apply on face, neck & décolleté.

Learn More

Frequently Asked Questions

See All Faqs

Why does HYDR/O include 7 molecular weights of Hyaluronic Acid?

HYDR/O delivers multi-depth hydration & different molecular sizes impact level of penetration. High molecular weight HAs hydrate surface layers of the skin, while lower weight HAs penetrate deeper layers of skin.

What is a colloid?

A colloid is made up of lipids dispersed through water, producing activated water. Bioactive Hydrolipid Fusion™ is a colloid made up of lipids & bioactive water.

What is TEWL?

TEWL, or transepidermal water loss, is the natural process of water evaporating from the skin's surface. Increased TEWL is a sign of a weakened or damaged skin barrier leading to symptoms such as dryness, tightness & flakiness.

What is the tool attached to the lid of HYDR/O?

For hygienic application, HYDR/O comes with a red spatula that uniquely attaches to the lid magnetically. This is for safe-keeping & helps protect from countertop cross-contamination.

When should I use HYDR/O?

HYDR/O can be used morning & evening as the final step in your skincare routine. Apply after serums & treatments to help replenish hydration, strengthen the skin barrier & increase the effectiveness of the actives in the other treatment products.

Do I use HYDR/O before or after InstaFacial® Plasma, Infusion, or Emulsion?

HYDR/O should be applied after treatment products such as InstaFacial® Plasma, Infusion + Emulsion. Its biomimetic hydration technology helps lock in moisture and support optimal absorption while strengthening the skin barrier.

Is HYDR/O a moisturizer?

HYDR/O is more than a traditional moisturizer. Powered by patent-pending Bioactive Hydrolipid Fusion™, it combines skin-identical lipids, Natural Moisturizing Factors & multi-depth hydration technology to help attract, retain, regulate & protect moisture while supporting barrier health & microbiome balance.

Can I use HYDR/O with retinoids?

Yes, HYDR/O was designed to complement active treatments, including retinoids. Its biomimetic lipids, ceramides & hydration technology help support barrier function & skin comfort while minimizing dryness associated with active ingredients.

Who is HYDR/O best suited for?

HYDR/O is suitable for all skin types, including dry, dehydrated, sensitive, compromised, & aging skin. Its lightweight, fast-absorbing formula delivers lasting hydration without feeling heavy or greasy.

See All Faqs

COMPLETE THE ROUTINE

Overall rating: 4.7 / 5 from 90 reviews.

AI Generated Review Summary

HYDR/O offers deep and instant hydration, leaving skin feeling soft and supple. Customers appreciate its nourishing properties and innovative packaging. While some find the scent polarizing, the product's texture and magnetic spatula are highly praised.

Summary topics

  • Skin Feel: 40%
  • Packaging Appeal: 37%
  • Product Texture: 12%
  • Magnetic Spatula: 19%
  • Skin Hydration: 37%

Review topics: ["fragrance","results","quality","scent","feels","ingredients","design","price","texture","skin","packaging","lines","looks","bottle","hydration","use","container","face","residue","difference","formula","compliments","glow","cream","moisturizer","spoon","spatula","scoop","skincare","addition"].

Review highlights

  • "The hydration is perfect (not too heavy/not too light) and my skin looks glowy and younger." — Lauren W.
  • "The packaging is so luxe and pretty, the little red magnetic spatula is super cute." — Gina M.
  • "I am a moisturizer snob with naturally dry and dull skin and this is the most perfect hydrating, silky smooth formula." — Micaela

Reviews

Nice lotion, love it on my counter, not sure it’s anything groundbreaking

"I do like this lotion, I started using Dr. Diamond products about 3 weeks ago. I got the insta facial and this before a trip, hoping that I would see immediate texture boost when wearing it. The products makeup skin very soft immediately, but I wouldn’t say I immediately see crepey texture go away or more bouncy looking skin. We’ll see if I notice results with longer use, but for the price & hype I was hoping for some sort of ingenious day-of benefit too!"

— Eva S. (4/5)

Worth every penny

"I love all Dr Diamonds products and use them all. If I only was able to purchase one it would be this cream. Super Hydrating, love the texture. I’ve been using this for over 6 months and have seen a difference in my skin overall."

— Laura (5/5)

Best hydrator

"My skin is soft, hydrated, bouncy and glowing after a few days use. Must have for any routine."

— Tallen (5/5)

Amazing Products for Mature Skin

"I love the entire line of Metacine products. They are amazing in terms of fine line elimination and the replenishment of hydration in my "mature" skin. I'm trying to "age with grace" and Dr. Diamond's regime is helping achieve that goal!"

— Dena M. (5/5)

First time user

"I recently tried Dr Metacine’s products. I LOVE them! My skin is hydrated and glowing after using for only a couple of weeks"

— Kimberly M. (5/5)

Best Hydrating Moisturizer!

"So very happy with this product. I have very dry skin and this moisturizer has solved that problem in conjunction with my other Dr Diamond products . Best skincare line ever !"

— Leslie (5/5)

5 ***** ‘s and beyond !!!!

"I will admit to being a lifelong skin care product junkie . . for over 30 years. I have tried several top-of-the-line products ,see my dermatologist regularly, have frequent laser treatments and take excellent care of my skin. When I started reading about this line it appealed to me because of the simplicity and also because of gentle yet highly effective retinol product included . I truly am blown away by all these products and particularly this Hydro moisturizer. . it is soothing and calming , rich without being sticky . It leaves an amazing glow as well . . i am absolutely in love with it ! I highly recommend this product and the whole routine . . 🙌"

— Leslie (5/5)

Still on the fence

"Although I love the feel of this product, I keep getting white heads after use and this is the only product addition. I will continue to use this in my routine and chalk it up to my skin purging."

— Debbe (4/5)

Amazing product

"I am 65 and just had a facial , the comment I got was you have amazing skin what are you using!! I told her all your products have made a big difference in my skin . Worth every penny ."

— Dena W. (5/5)

"The product is amazing but the container size is too small for that much $$."

— Veronika (4/5)

Q&A