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Translation missing: en.INSTAFACIAL® COLLECTION TRIO

INSTAFACIAL® COLLECTION TRIO

InstaFacial® Plasma + Infusion + Emulsion

Key Benefits
  • Repair & Rejuvenate: supports skin’s natural renewal processes for healthier, more youthful-looking skin
  • Brightening: reduces appearance of hyperpigmentation for a brighter complexion
  • Lift, Firm & Define: microcollagen peptides visibly plump & hydrate the skin, improving the appearance of double chin & facial sagging
  • Structural Support: supports collagen synthesis, for more defined & sculpted skin
  • Resurface & Renew: bioactive retinoid gently resurfaces to improve the look of uneven tone & texture
  • Non-irritating: next-generation, direct-acting retinoid delivers potent results with less irritation than traditional retinoids
  • Tone & Texture: gently resurfaces skin, improving the appearance of uneven tone & texture
  • Non-greasy finish that absorbs seamlessly & layers beautifully under makeup
  • Vegan & Fragrance-Free: designed for all skin types, including sensitive skin

Description

The complete InstaFacial® routine. Inspired by three key steps of Dr. Diamond's signature InstaFacial®, this transformative trio combines bioengineered growth factors, next-generation retinoid technology & human-identical microcollagen peptides to support cellular communication, renewal & collagen synthesis.

Together, Plasma, Infusion + Emulsion work synergistically to improve firmness, texture, tone, hydration & overall skin quality for healthier, more radiant skin.

Key Ingredients
  • Five Different Types of Bioengineered Growth Factors in Plasma: supports cellular renewal, healing & collagen, elastin & hyaluronic acid production
  • Copper Tripeptide-1 in Plasma: naturally found in human plasma, stimulates skin renewal & fades hyperpigmentation & sun damage over time for a brighter complexion
  • Botox-like Peptide (Acetyl Hexapeptide-8) in Plasma: relaxes facial muscles, reducing appearance of fine lines & wrinkles
  • Biomimetic Microcollagen Matrix in Infusion: a proprietary network of three microcollagen peptides that support collagen synthesis, firmness, elasticity & overall skin structure
  • Signaling Peptides in Infusion: a network of signaling peptides work to firm the dermal layer, boost hydration, support collagen production & reinforce skin’s structural integrity
  • Hydroxypinacolone Retinoate (HPR) in Emulsion: a next generation bioactive retinoid that resurfaces & renews without metabolic conversion, making it gentler on skin while maintaining potency
  • Myristoyl Nonapeptide-3 in Emulsion: a biomimetic, anti-aging peptide designed to mimic the effects of retinoic acid to support cell turnover & collagen production without irritation

View Full List

PLASMA
O WATER ● GLYCERIN O 1,2-HEXANEDIOL ● NICOTIANA BENTHAMIANA HEXA-PEPTIDE-40 SH-OLIGOPEPTIDE-1 ● N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATE ● SH-OLIGOPEPTIDE-1 ● SH-OLIGOPEPTIDE-2 ● SH-POLYPEPTIDE-1 ● SH-POLYPEPTIDE-11 ● SH-POLYPEPTIDE-9 ● ACETYL HEXAPEPTIDE-8 ● ACETYL GLUTAMINE ● COPPER TRIPEPTIDE-1 ● RAPHANUS SATIVUS (RADISH) ROOT EXTRACT ● BACILLUS/FOLIC ACID FERMENT FILTRATE EXTRACT O HYDROXYACETO-PHENONE O DISODIUM ACETYL GLUCOSAMINE PHOSPHATE O SODIUM GLUCURONATE ● SODIUM HYALURONATE O SODIUM PHYTATE O MAGNESIUM SULFATE O HYDROXYETHYL-CELLULOSE O LECITHIN OCITRIC ACID O MALTODEXTRIN O PROPANEDIOL ● BUTYLENE GLYCOL O PENTYLENE GLYCOL O ETHYLHEXYLGLYCERIN ● CAPRYLYL GLYCOL O PHENOXYETHANOL

INFUSION
O WATER ● GLYCERIN O DIMETHICONE O PENTYLENE GLYCOL O PROPANEDIOL ● NIACINAMIDE O SIMMONDSIA CHINESIS (JOJOBA) SEED OIL ● GIARTINA STELLATA EXTRACT ● SOLUBLE PROTEOGLYCAN ● MYRISTOYL PENTAPEPTIDE-11 ● SH-POLYPEPTIDE-121 ● SH-POLYPEPTIDE-123 ● SR-(SH-POLYPEPTIDE-69 DIPEPTIDE-19) ● ACETYL TRIPEPTIDE-108 N-ACETYL LYSYL GLUTAMINE ● MYRISTOYL PENTAPEPTIDE-8 O SQUALANE ● SODIUM HYALURONATE O TREHALOSE ● DIAMOND POWDER O DIMETHICONE CROSSPOLYMER ● BETA-GLUCAN ● HORDEUM VULGARE SEED EXTRACT O PHOSPHOLIPIDS O XANTHAN GUM O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMEHTYL TAURATE COPOLYMER O BUTYLENE GLYCOL O POLYSORBATE 60 O PHENOXYETHANOL O CAPRYLYL GLYCOL O CHLORPHENESIN O 1,2-HEXANEDIOL O SODIUM BENZOATE O GLYCERYL CAPRYLATE O GLYCERYL UNDECYLENATE O POTASSIUM SORBATE

EMULSION
O WATER O DIMETHICONE ● GLYCERIN O BUTYLENE GLYCOL O DIMETHICONE CROSSPOLYMER ● NIACINAMIDE O HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER O MACADAMIA INTEGRIFOLIA SEED OIL ● NICOTIANA BENTHAMIANA HEXAPEPTIDE-40 SH-OLIGOPEPTIDE-1 ● MYRISTOYL NONAPEPTIDE-3 ● PALMITOYL TETRAPEPTIDE-7 ● PALMITOYL TRIPEPTIDE-38 O CAMELLIA SINENSIS LEAF EXTRACT O DIMETHICONE/PEG-10/15 CROSSPOLYMER ● SODIUM HYALURONATE CROSSPOLYMER ● SODIUM ACETYLATED HYALURONATE ● HYDROLYZED SODIUM HYALURONATE ● SODIUM HYALURONATE ● HYDROXYPINACOLONE RETINOATE ● TOCOPHERYL ACETATE O PHOSPHOLIPIDS O SODIUM PHYTATE ● SQUALANE ● CYCLIC LYSOPHOSPHATIDIC ACID ● SODIUM CARBOXYMETHYL BETA-GLUCAN ● GLYCYRRHETINIC ACID O LECITHIN O DIMETHICONOL O CITRIC ACID O HYDROXYPROPYL CYCLODEXTRIN O DIMETHYL ISOSORBIDE O PENTYLENE GLYCOL O CAPRYLYL GLYCOL O ETHYLHEXYLGLYCERIN O CHLORPHENESIN O POLYSORBATE 60 O PHENOXYETHANOL

How to Use

AM After cleansing, gently press 2-3 drops of Plasma on face, neck & décolleté. Follow with 1-2 pumps of Infusion on slightly damp skin. Use 
on face, neck & décolleté.

PM Apply Plasma & Infusion as instructed in the AM. After, use 1 pump of Emulsion & apply thin layer to face, neck & décolleté.

Optimal Results: Finish with HYDR/O in AM + PM to seal in actives.

Discovery size products are final sale & non-returnable.

Pairs well with

Translation missing: en.HYDR/O

HYDR/O

2 Sizes
$35 - $300
Translation missing: en.EyeLift

EyeLift

2 sizes
$50 - $225
Translation missing: en.INSTAFACIAL® PLASMA

INSTAFACIAL® PLASMA

3 sizes
$35 - $200
Translation missing: en.INSTAFACIAL® INFUSION

INSTAFACIAL® INFUSION

2 sizes
$40 - $325
Translation missing: en.INSTAFACIAL® EMULSION

INSTAFACIAL® EMULSION

3 sizes
$50 - $350
Translation missing: en.INSTAFACIAL® TRIO DISCOVERY SET

INSTAFACIAL® TRIO DISCOVERY SET

1 size
$125
Translation missing: en.INSTAFACIAL® COLLECTION DUO

INSTAFACIAL® COLLECTION DUO

2 sizes
$85 - $550

CLINICALLY PROVEN.
BACKED BY SCIENCE.

In an independent clinical trial with participants representing all skin types of the Fitzpatrick scale with skin objectively graded by a clinical investigator & using the highest standing of instrumentation. The subjects also provided self assessments.

Plasma + Emulsion: Before & Afters shown at 8 weeks.
Infusion: Before & Afters shown at 12 weeks.

  • 94% had improvement in crow’s feet lines after 8 weeks.1
  • 91% reported their skin looked firmer & lifted after 8 weeks.2
  • 91% reported smoother & more refined skin texture after 4 weeks.2
  • 83% reported healthier looking & more youthful skin after 4 weeks.2
  • 83% reported skin looked more luminous & radiant after 8 weeks.2

Forehead Wrinkles

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Brightness & Hyperpigmentation

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Fine Lines - Crow's Feet

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Fine Lines - Crow's Feet

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INFORMED BY MEDICINE. MADE WITH TECHNOLOGY.

  • CLINICAL INSPIRATION

    The InstaFacial® Trio is inspired by three of the most transformative steps of Dr. Diamond's signature InstaFacial® in clinic treatment. Plasma draws inspiration from platelet-rich plasma (PRP), Emulsion from laser resurfacing & Microneedling + Infusion from the final medical-grade micronized collagen mask treatment. Together, they translate the principles of regenerative aesthetics into a comprehensive at-home routine designed to support healthier, firmer & more youthful-looking skin.

  • THREE PATHWAYS

    Healthy skin depends on a sophisticated network of biological processes working in harmony. Cellular communication helps coordinate repair & rejuvenation, cellular renewal helps improve texture, tone & collagen architecture provides the structural foundation responsible for firmness & elasticity. The InstaFacial® Trio was designed to support each of these essential pathways. Plasma helps optimize cellular communication, Emulsion supports renewal & resurfacing + Infusion helps reinforce the skin's collagen network & structural integrity.

  • MOLECULAR SYNERGY

    The most effective rejuvenation occurs when multiple biological pathways are supported simultaneously. Plasma helps support the signals responsible for repair & rejuvenation. Emulsion helps optimize cellular turnover & resurfacing. Infusion helps reinforce the collagen architecture that provides skin with strength, elasticity & resilience. Working together, these technologies create a synergistic system that supports healthier skin function at every level. The result is a more comprehensive approach to rejuvenation than any individual technology could achieve alone, delivering visible improvements in firmness, texture, radiance & overall skin quality over time.

A MULTI-PATHWAY APPROACH
TO REJUVENATION.

See The Science
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  • CELLULAR COMMUNICATION

    Inspired by the regenerative properties of platelet-rich plasma (PRP), InstaFacial® Plasma features five different types of bioengineered, human-identical growth factors that support cellular communication, collagen production, nutrient delivery & skin renewal to reduce the appearance of fine lines & wrinkles & promote a firmer, healthier-looking complexion.

  • RESURFACE & RENEW

    These two ingredients were intentionally paired in InstaFacial® Emulsion to support skin renewal through different yet complementary mechanisms. HPR supports cellular turnover by directly binding with retinoid receptors without metabolic conversion, which traditional retinoids go through. By bypassing this pathway, HPR supports renewal without the side effects of peeling & irritation.

    Myristoyl Nonapeptide-3 reinforces rejuvenation pathways through peptide signaling & by working with HPR, the two ingredients create a more comprehensive approach to visible skin renewal.

  • BARRIER OPTIMIZATION

    Niacinamide is a multi-functional Vitamin B3 that strengthens the skin barrier, improves the appearance of uneven tone & texture & supports a smoother, brighter, more resilient complexion. In InstaFacial® Emulsion, niacinamide works synergistically with HPR, Niacinamide supports skin renewal wile strengthening the barrier without sensitizing the barrier.

  • ZERO COMPROMISE

    Hydration & barrier integrity play a critical role in skin rejuvenation. A complex of four molecular weights of hyaluronic acid, combined with niacinamide, lipopeptides & squalane, helps replenish moisture, strengthen the barrier & support skin resilience. A strong barrier is the foundation that creates the optimal conditions for cellular renewal, repair & collagen production.

  • STRUCTURE SUPPORT

    A proprietary network composed of three bioengineered, human-identical microcollagen peptides designed for optimal skin recognition & absorption. These advanced peptides support the synthesis of Types I & III collagen (I provides structural & tensile strength while III supports flexibility & elasticity), which are the types most closely associated with youthful, healthy-looking skin. In an ex-vivo human skin study, the Microcollagen Matrix (MCM-3) was shown to increase key collagen markers, supporting firmer, smoother & more resilient-looking skin.

See The Science

A ROUTINE ENGINEERED FOR RESULTS.

INSTAFACIAL® PLASMA

Bioactive Growth Factor Serum

A serum inspired by platelet-rich plasma (PRP), a key modality in the Diamond InstaFacial®, featuring five different types of bioengineered, human-identical growth factors, signaling peptides & hyaluronic acid to support the skin's natural repair & rejuvenation.

HOW TO USE: After cleansing, gently press 2-3 drops on slightly damp skin. Apply on face, neck & décolleté.

Learn More

Frequently Asked Questions

See All Faqs

Why are Plasma, Emulsion + Infusion paired together?

The Trio is inspired by three key steps of Dr. Diamond's signature in-clinic InstaFacial®, each representing a different treatment modality. Plasma is inspired by platelet-rich plasma (PRP), Emulsion by laser resurfacing & Infusion by the final micronized collagen mask. Together, they bring the principles of regenerative aesthetics into a complete at-home routine, creating a synergistic system designed to support healthier, firmer & more radiant skin.

How is the Trio different from using a single treatment product?

The Trio supports multiple biological pathways involved in skin rejuvenation simultaneously. By combining growth factors in Plasma, direct-acting retinoid technology in Emulsion & bioengineered microcollagen peptides in Infusion, it provides a more comprehensive approach to visible skin improvement than any individual technology alone.

Is the InstaFacial® Trio suitable for sensitive skin?

Yes. Plasma, Infusion + Emulsion are all suitable for sensitive skin. Because Emulsion contains a bioactive retinoid, those new to retinoids or with sensitive skin may wish to introduce Emulsion gradually (2-3 nights a week) before increasing to nightly use.

Can I use the InstaFacial® Trio after a cosmetic procedure?

Plasma + Infusion are excellent options for supporting skin during the recovery process. Inspired by regenerative medicine, Plasma is formulated with five different types of bioengineered, human-identical growth factors & advanced signaling peptides, including Copper Tripeptide-1, to help support the skin's natural repair & renewal processes. Infusion features a proprietary Biomimetic Microcollagen Matrix designed to support collagen synthesis, hydration, firmness & overall skin resilience. Because Emulsion contains a bioactive retinoid, we recommend discontinuing use approximately 10 days prior to a procedure and waiting until the skin has sufficiently healed, typically about 10 days post-procedure, before reintroducing it into your routine. As every procedure & recovery timeline is different, we always recommend following your physician's post-treatment instructions.

Do I need HYDR/O with the Trio?

While the Trio provides significant rejuvenating & hydrating benefits, we recommend adding a moisturizer after Emulsion to seal in the benefits of all treatments. HYDR/O can be added to help strengthen the skin barrier, support microbiome health & lock in moisture for a more complete skincare routine & helps improve the effectiveness of the actives applied prior.

Can I use your products while pregnant or breastfeeding?

If you are pregnant, planning to become pregnant, or breastfeeding, we recommend consulting your physician before introducing any new skincare products into your routine.

Are your products fragrance-free?

Yes, Dr. Diamond's Metacine products are formulated without added fragrance. Inspired by the needs of patients in Dr. Diamond's clinical practice, our formulas are developed with a focus on efficacy, skin compatibility & supporting healthy skin function.

What does "human-identical" mean?

Human-identical ingredients are bioengineered to mirror the structure & function of molecules naturally found in the human body. This allows them to work in harmony with the skin's biology while maintaining the highest standards of safety & consistency.

Are your growth factors human-derived?

No, our growth factors are bioengineered & human-identical, meaning they are designed to mimic naturally occurring human growth factors without being derived from human tissue, blood, or cells.

See All Faqs

COMPLETE THE ROUTINE

Overall rating: 4.850746 / 5 from 201 reviews.

AI Generated Review Summary

The INSTAFACIAL® COLLECTION TRIO is praised for its significant skin rejuvenation effects, making skin feel silky smooth, look fresh and youthful, and reduce fine lines. Customers also appreciate the product's simple and sophisticated packaging, though opinions on the scent vary.

Summary topics

  • Skin Difference (11%): It was reported by customers that they noticed a significant difference in their skin after using the product.
  • Face Appearance (7%): Customers expressed satisfaction with the ability of this product to make their face look clean and youthful.
  • Skin Look (10%): Customers raved about how the infusion serum made their skin look fresh, plumper, and radiant.
  • Packaging Design (20%): A significant number of customers loved the packaging, describing it as simple, sophisticated, and beautiful.
  • Product Results (15%): Many customers raved about the amazing and noticeable results they saw with this product, making it a top choice.

Review topics: ["feels","packaging","skin","scent","results","texture","looks","shipping","face","improvement","glow","price","size","bottle","ingredients","lines","wrinkles","quality","reduction","difference","irritation","appearance","effects","trio","complexion","magic","power","skincare","hydration","consistency"].

Review highlights

  • "The Infusion has very light scent and light texture as well." — Katherine E.
  • "Each product works beautifully together to deliver noticeable results—my complexion looks fresher and more radiant." — Tina S.
  • "Amazing products that make your skin feel incredible and look incredible!" — Ria

Reviews

"I’m trying the system for the first time so I need to give it time to see if there are results. I do like the fast delivery and how they package the products."

— Kim (5/5)

Loved all the products!

"I loved this discovery set! I was impressed with the products and the amount of each. Definitely will be buying the plasma again and the others as I can afford them! Skin felt great with them, and none of the products caused an increase in acne."

— Jessica (5/5)

Radiance in Three Steps

"I just started using the Instafacial Collection Trio, and I'm genuinely impressed with how my skin is responding. The texture has become noticeably smoother, my complexion looks brighter, and there's a healthy, radiant glow that wasn't there before. My skin feels softer, looks more refined, and even without makeup it has a fresh, luminous appearance. It's definitely become my favorite skincare routine."

— Pamela N. (5/5)

Hopeful but need to keep using to see if it’s worth it

"I was hoping for some day-of plumping or crepey coverage with this set— It makes my skin very soft and I like the texture, but it seems the benefit is supposed to come from repeated use. It’s very expensive so I’ll only keep using it if I see very clear results."

— Eva S. (4/5)

My house keeper noticed.

"I have been using the “best of the best“ products from my family, who are very involved with spas and special skin products. I didn’t realize that I was the “odd woman out” since I was not Canadian with their beautiful white skin and I had lived near the beach in Florida since I was 16 years old. Needless to say, I need all the help I can get!"

— Lisa Y. (5/5)

Better than expected

"My skin has never looked better. I was already getting compliments just after a few days use."

— Tallen (5/5)

Amazing products that work quickly.

"Usually new products take a few weeks to show any results if any at all; however after only three days I noticed that my face was tighter. These products were extremely expensive, but now I understand why."

— Diana C. (4/5)

Loving my skin and this line of skincare!

"I'm 57 and have generally good skin so I wasn't sure I was going to notice a difference. Immediately can tell my skin glows and the texture has improved! Love this line!"

— Kristine D. (5/5)

Best skin care ever

"This is the best skin care I have ever seen, I have used ZO, SkinMedic and by far these products by Dr. Diamond, you see results quickly. Will never stop using his products."

— Toni L. (5/5)

Game Changer

"I’ve been consistently using the Instafacial Collection Trio for over a year and have really noted a marked improvement in my skin. It has not only helped improve texture, but has also made my skin look at feel plumper, which is much needed over 55. I do not use fillers and feel that this skin care line has helped me get away without needing to. Highly recommend this line!"

— JM (5/5)

Q&A